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Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Diagnosis

Your doctor will use imaging studies and other specialized tests to diagnose CTEPH. These tests can include:

  • Transthoracic echocardiogram (TTE) uses sound waves (ultrasound) to create a moving picture of the heart and lungs. During this test your doctor can screen for pulmonary hypertension by looking for specific changes to the size of your heart and blood flow in the lungs that occur in CTEPH.
  • Ventilation-perfusion (V/Q) scan uses radioactive material that is both inhaled and injected into the blood to measure airflow and blood flow through the lungs.
  • Computed tomography (CT) pulmonary angiography is used to show blood flow through the lungs and to detect pulmonary embolism. During this test, dye (contrast material) is injected into the blood vessels and a CT (computed tomography) scan is used to take pictures of blood as it flows through the lungs.  
  • Right heart catheterization uses a catheter (long thin flexible tube) that is inserted through a vein in the leg, arm or neck and guided to the right side of the heart to provide a closer look at the pulmonary artery, which delivers blood from the heart to the lungs. Using this approach your doctor can check blood pressure to see if blood is "backing up" and damaging the heart or lungs.
  • Pulmonary angiography is a minimally invasive procedure that uses a catheter (a long, thin flexible tube) inserted into a blood vessel in the leg, arm or neck to take X-ray pictures of the heart and pulmonary artery. Contrast dye is used to make it easier to see and evaluate the artery. A pulmonary angiography is performed if abnormal results are found on a V/Q scan and is used to confirm constricted blood flow through the lungs.
  • Cardiopulmonary exercise testing uses either an EKG or right heart catheterization to measure the heart and lungs’ response to exercise. This will help your doctor determine if you have a subtle case of CTEPH.
  • Pulmonary function tests refer to a series of breathing tests that measure lung capacity and mechanics to determine if there’s a problem with your lungs.